May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Indocyanine Green Angiography Features of Central Areolar Choroidal Dystrophy
Author Affiliations & Notes
  • B. Guigui
    Intercommunal de Creteil, Paris, France
  • O. Semoun
    Intercommunal de Creteil, Paris, France
  • G. Querques
    Intercommunal de Creteil, Paris, France
  • G. Coscas
    Intercommunal de Creteil, Paris, France
  • G. Soubrane
    Intercommunal de Creteil, Paris, France
  • E. H. Souied
    Intercommunal de Creteil, Paris, France
  • Footnotes
    Commercial Relationships  B. Guigui, None; O. Semoun, None; G. Querques, None; G. Coscas, None; G. Soubrane, None; E.H. Souied, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4672. doi:https://doi.org/
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      B. Guigui, O. Semoun, G. Querques, G. Coscas, G. Soubrane, E. H. Souied; Indocyanine Green Angiography Features of Central Areolar Choroidal Dystrophy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4672. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Central areolar choroidal dystrophy (CACD) is an inherited autosomal dominant macular disease characterized by a central atrophy of the retinal pigment epithelium and choriocapillaris. Our purpose was to describe fluorescein angiography (FA) and confocal indocyanine green angiography (ICGA) features of CACD.

Methods: : We performed a complete ophthalmologic examination including best corrected visual acuity (BCVA), fundus examination, color fundus photographs, red free frames, FA, infrared, confocal ICG and electroretinography, in a cohort of patients with family history of CACD.

Results: : Eleven patients (22 eyes) affected were prospectively included. ICG differentiated two distinct phenotypes. In 9/11 patients, atrophy area was hyperfluorescent or normofluorescent. In the two other patients, the lesion was hypofluorescent from early to late phases and pin points were observed on the late phases.

Conclusions: : In our small series, ICG angiography distinguished two phenotypes of CACD, correlated with FA features.

Keywords: macula/fovea • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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