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B. Guigui, O. Semoun, G. Querques, G. Coscas, G. Soubrane, E. H. Souied; Indocyanine Green Angiography Features of Central Areolar Choroidal Dystrophy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4672.
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© ARVO (1962-2015); The Authors (2016-present)
Central areolar choroidal dystrophy (CACD) is an inherited autosomal dominant macular disease characterized by a central atrophy of the retinal pigment epithelium and choriocapillaris. Our purpose was to describe fluorescein angiography (FA) and confocal indocyanine green angiography (ICGA) features of CACD.
We performed a complete ophthalmologic examination including best corrected visual acuity (BCVA), fundus examination, color fundus photographs, red free frames, FA, infrared, confocal ICG and electroretinography, in a cohort of patients with family history of CACD.
Eleven patients (22 eyes) affected were prospectively included. ICG differentiated two distinct phenotypes. In 9/11 patients, atrophy area was hyperfluorescent or normofluorescent. In the two other patients, the lesion was hypofluorescent from early to late phases and pin points were observed on the late phases.
In our small series, ICG angiography distinguished two phenotypes of CACD, correlated with FA features.
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