MP-1 Nidek vs. Spectral OCT/SLO OTI Microperimeter on the Evaluation of Retinal Sensibility in Different Macular Diseases

Abstract

Purpose: : Prospective comparative observational study to measure diagnostic efficacy and availability of new OCT/SLO microperimetry OTI compared to MP1 NIDEK microperimeter.

Methods: : 40 eyes of 25 consecutive patients underwent a complete ophthalmologic examination with ETDRS BCVA and OCT evaluation. We classified eyes in 3 Groups according to the considered pathologies: 18 eyes with diabetic macular edema (different patterns: sponge like, diffuse, serous foveal detachment), 10 with idiopathic macular holes and 12 with macular pucker . Each eye was studied on both microperimetry instruments and a specified strategy was performed according to the pathological feature. Location and stability of fixation as well as depth and size of detected scotomata were compared on both instruments.

Results: : The evaluation of macular fixation was not statistically different with both instruments in all Groups: a stable fixation was detected in 25 eyes in MP1 and 23 eyes in OTI. All over mean macular sensitivity was 12.3 dB with SLO and 13.3 dB with MP1. There was good concordance of results between the considered instruments in each specified Group, with 87.5% (35/40) eyes examined showing equal defects. Average number of stimuli was similar in both instruments on different studies applied (48.2 on MP1 and 45.7 on OTI); examination time was prolonged with MP1 (14.4 min on OTI - 18.5 min on MP1). Throughout all examinations, fundus visualization with the SLO was superior to standard MP1 (besides its optional fundus colour camera).

Conclusions: : Our new OCT/SLO microperimetry instrument represents nowadays a valid and useful alternative to MP1, despite its less diffusion and less protocol standardization. This instrument has moreover the possibility to directly visualize the results of microperimetry overlapped on a OCT retinal thickness map, for an intuitive comprehension of the entity and extension of the pathology.

Keywords: macula/fovea • perimetry • imaging/image analysis: clinical