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P. M. Garcia, G. Landa, R. B. Rosen; Correlation of Retinal Thickness and Microperimetry Testing in Patients With Central Serous Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4710.
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The OTI Spectral OCT/SLO has been used for B-scan imaging and retinal thickness analysis since 2006. Recently, a Microperimetry Module has been added to the system, allowing a determination of the patients’ ability to discriminate stimuli of varying intensity over a predetermined area.The purpose of this study was to investigate a correlation between the retinal thickness measurements and microperimetry findings in patients with Central Serous Retinopathy (CSR).
A retrospective analysis was performed on patients with CSR who were imaged with the OTI Spectral OCT/SLO with Microperimetry on at least 2 separate occasions between September 2006 and November 2007. At every visit, OCT/SLO B-scans, retinal thickness evaluation and microperimetry testing were performed.The change in retinal thickness was determined using the retinal thickness comparison function. For microperimetry, the change in threshold intensity was automatically generated. The average change in thickness was compared to the average change in threshold intensity to determine if a correlation exists between the two tests in patients with CSR.A separate evaluation of neuroretinal thickness overlaying the subretinal fluid was determined manually using the horizontal calipers on the OCT/SLO B-scans at the thinnest part of the fovea.
A total of eight patients (9 eyes) were included in the study. Twenty six (26) comparisons were made, and no correlation was found between retinal thickness and microperimetry findings.Automated retinal thickness calculations, which measured the distance between the RNFL to the RPE, showed change in retinal thicknes in 73% (19/26) patients, however neuroretinal thickness was unchanged (less than 10 microns) in 96% (25/26) cases.Average change in threshold perimetry was unchanged (less than 2dB) in 85% (22/26).
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