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Z. Michalewska, J. Michalewski, R. Adelman, J. Nawrocki; Macular Hole Formation Visualized With Spectral Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4711. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To study the process of macular hole formation and vitreoretinal abnormalities in the fellow eyes of macular hole.
Serial Spectral Optical Coherence Tomography (SOCT) examinations were performed 4 times during 6 months study period in 131 patients. Foveal and vitreo retinal abnormalities were recorded in the fellow eyes of macular hole. The progress of abnormalities was studied.
The following abnormalities were observed in the fellow eye: posterior hyaloid detachment (9 eyes), partial posterior hyaloid detachment (15 eyes), posterior hyaloid condensation (6 eyes), foveal contour irregularities (17 eyes), vitreo macular traction syndrome (5 eyes), epiretinal membranes (18 eyes, lamellar hole (6 eyes). Evolution to full thickness macular hole was noted in 5 eyes, one of these eyes had previous cystic space, and four had previous elevation of the foveal center./>
SOCT is capable of detecting early stages of macular hole formation. Elevation of foveal center is an early phase of macular hole formation and often progress to full thickness macular hole. There is high prevalence of vitreoretinal abnormalities in fellow eyes. Evolution of these disorders suggest that abnormalities of vitreoretinal interface may have similar pathogenesis.
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