Abstract
Purpose: :
To evaluate the clinical response with autologous serum treatment in patients with vernal keratoconjunctivitis.
Methods: :
This is a longitudinal, prospective and experimental study of cases with vernal keratoconjunctivitis refractive to conventional treatment. Patients were treated with topical autologous serum at 20% every 4 hours. Clinical symptoms and signs were reported before treatment and every week with autologous serum drops. We designed a questionnaire and photographic guide to evaluate treatment response in each patient objectively. Follow up study was one month.
Results: :
We included 20 eyes of 10 patients with vernal keratoconjunctivits, with a mean average of 9.4 years old 8 were male and 2 were female. The response to treatment with autologous serum was a decrease of 78.13% of the symptoms and 66.27% percent of signs at one month follow up. No adverse effects were presented.
Conclusions: :
Autologous serum can be an alternative treatment in vernal keratoconjunctivitis with important decrease of signs and symptoms without adverse effects of conventional therapies.
Keywords: cornea: clinical science • conjunctivitis