May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Assessment of Macular Pigment Optical Density: Metropsis Versus Macuscope
Author Affiliations & Notes
  • M. J. Perez Carrasco
    Optica II, Escuela Univ de Optica, Madrid, Spain
    Optica II, Universidad Complutense, Madrid, Spain
  • A. R. Barrio
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • C. Palomo
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • M. Muñoz
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • D. Rios
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • R. Sanchez
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • C. Puell
    Optica II, Escuela Univ de Optica, Madrid, Spain
  • Footnotes
    Commercial Relationships  M.J. Perez Carrasco, None; A.R. Barrio, None; C. Palomo, None; M. Muñoz, None; D. Rios, None; R. Sanchez, None; C. Puell, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4955. doi:
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      M. J. Perez Carrasco, A. R. Barrio, C. Palomo, M. Muñoz, D. Rios, R. Sanchez, C. Puell; Assessment of Macular Pigment Optical Density: Metropsis Versus Macuscope. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4955.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare macular pigment optical density using two new different heterochromatic flicker photometer devices.

Methods: : We measured macular pigment (MP) optical density at the fovea in 40 healthy young subjects using a screening non-invasive minimum flicker photometer device (Macuscope, Macuvision Europe, LTD) and the Metropsis test (Cambridge Research Systems) that is based in the apparent motion photometry method and employs a CRT monitor for stimulus presentation.

Results: : The mean macular pigment optical density measured using the Macuscope was 0.438 ± 0.17, and that using the Metropsis was 0.396 ± 0.14. The 95% confidence interval for the mean difference was 0.024 to 0.108. We found a significant correlation (Pearson’s correlation= 0.39; p< 0.0125) between Macuscope and Metropsis systems (PMmetropsis = 0.25 + 0.32 x PM macuscope; R2 = 15.31).

Conclusions: : As the 95% confidence interval for the mean difference contains 0, we conclude that there is, on average, no significant difference in measurements provided by these two new devices. The Metropsis test tends to underestimate macular pigment compared with the Macuscope.

Keywords: macular pigment • macula/fovea • discrimination 
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