May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Blood Pressure and Open Angle Glaucoma: The Los Angeles Latino Eye Study
Author Affiliations & Notes
  • F. Memarzadeh
    University of Southern California, Doheny Eye Institute, LA, California
    Department of Ophthalmology,
  • M. Ying-Li
    Department of Preventive Medicine, University of Southern California, LA, California
  • S. Azen
    University of Southern California, Doheny Eye Institute, LA, California
    Department of Ophthalmology and Preventative Medicine,
  • R. Varma
    University of Southern California, Doheny Eye Institute, LA, California
    Department of Ophthalmology and Preventative Medicine,
  • Footnotes
    Commercial Relationships  F. Memarzadeh, None; M. Ying-Li, None; S. Azen, None; R. Varma, None.
  • Footnotes
    Support  NEI U10-EY-11753 and EY-03040
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5053. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      F. Memarzadeh, M. Ying-Li, S. Azen, R. Varma; Blood Pressure and Open Angle Glaucoma: The Los Angeles Latino Eye Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5053. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To examine the relationship between blood pressure (BP) andthe risk of open angle glaucoma OAG in an adult Latino population.

 
Methods:
 

The Los Angeles Latino Eye Study (LALES) is a population-basedstudy of eye disease in Latinos aged 40 years or older. Participants(N=6130) underwent an interviewer-administered questionnaireand a complete ocular and clinical examination. The associationbetween age, intraocular pressure (IOP) and systolic and diastolicBP (SBP, DBP) was evaluated. Age-adjusted odds ratios (OR) werecalculated to assess the risk of OAG in relation to BP, perfusionpressures (PP) and other cardiovascular risk factors.

 
Results:
 

IOP increases as blood pressure increases. This increase issignificant for both systolic and diastolic BP (P< 0.001)and is independent of age. Elevated SBP and DBP are associatedwith increased risk of OAG (OR 2.0 and 2.5, respectively) asare low DBP (OR 1.6) and low SPP and DPP (OR 2.9 and 2.0, respectively).The strongest associations with OAG exist for high SBP (Figure1) and low DPP (Figure 2). There was no relationship betweenthe risk of OAG and the presence of other diseases of cardiovascularorigin.

 
Conclusions:
 

Elevated systolic blood pressures and low diastolic perfusionpressures are important risk factors for OAG.  

 

 
Keywords: clinical (human) or epidemiologic studies: risk factor assessment • intraocular pressure 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×