May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Novel Visualization Methods of Anterior Chamber Angle Using Three Dimensional Anterior Segment Optical Coherence Tomography
Author Affiliations & Notes
  • H. Mori
    Ophthalmology, Tokyo Medical University, Tokyo, Japan
  • Y. Watanabe
    Ophthalmology, Tokyo Medical University, Tokyo, Japan
  • Y. Yasuno
    Computational Optics Group, University of Tsukuba, Ibaraki, Japan
  • H. Goto
    Ophthalmology, Tokyo Medical University, Tokyo, Japan
  • Footnotes
    Commercial Relationships  H. Mori, None; Y. Watanabe, None; Y. Yasuno, None; H. Goto, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5079. doi:
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    • Get Citation

      H. Mori, Y. Watanabe, Y. Yasuno, H. Goto; Novel Visualization Methods of Anterior Chamber Angle Using Three Dimensional Anterior Segment Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5079.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To demonstrate a visualization methods of anterior chamber angle using three-dimensional cornea and anterior segment optical coherence tomography (3-D CAS-OCT).

 
Methods:
 

A prototype of 3-D CAS-OCT(TOMEY Corporation, Aichi, Japan) using a probe wavelength of 1,300nm based on swept-source OCT was emplyed in this study. The measurement range was 16 mm×16 mm, and a raster-scanning protocol with 256A-scans×256 B-scans was used. The scanning rate was 20,000 A lines/s, and the acquisition time for a three-dimensional tomography is 3.3s. Total 20 eyes of 18 patients with normal angle, narrow angle, corneal opacities and corneal grafting were examined. A custom made 3-D visualization protocols was applied to the 3-D tomograms obtained. These imaging protocols enables 360 degree rotating tomographic observation of the angle (rotation view) and 360 degree rotating imitate gonioscopic observation of the angle (gonioscopic view).

 
Results:
 

All 20 of 20 eyes, anterior chamber angles were clearly visualized by both of the rotation and the gonioscopic view. In particular, peripheral anterior synechia could be readily detected in the narrow angle cases. The methods clearly visualized the angle of the eye with severe corneal opacities, although standard gonioscope was not able to access the angles.

 
Conclusions:
 

The novel visualization methods of anterior chamber angle using 3-D CAS-OCT allows entire angle observation readily. These visualization methods successfully accessed the cases which was difficult to be examined by conventional gonioscopy.  

 
Clinical Trial:
 

www.umin.ac.jp/ctr/index/htm R000001087

 
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical • image processing 
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