Abstract
Purpose: :
To evaluate performance of a noncontact anterior segment optical coherence tomography (AS-OCT; VisanteTM, Carl Zeiss Meditec, Dublin, CA) in anterior chamber configuration of Japanese and to assess the factors relating to obtained parameters.
Methods: :
Measurements with AS-OCT were performed consecutively in 322 right eyes of 322 subjects (142 women aged 61.6±12.9 yrs and 180 men aged 59.4±12.3 yrs) having no history of previous ocular surgery including laser treatment. The parameters analyzed were central anterior chamber depth (ACD), angle opening distance at 500 µm from the scleral spur (AOD500), and anterior chamber angle (ACA).
Results: :
Measurements were successfully done in 304 (94.4%) of 322 eyes. Between men and women, age and refraction showed no significant difference (P>0.1, Mann-Whitney test), while significant differences in ACD (2.77±0.44 vs. 2.66±0.41 mm, P=0.01), AOD500 in temporal (0.29±0.12 vs. 0.26±0.15mm, P=0.03) and in nasal (0.30±0.13 vs. 0.27±0.13 mm, P=0.03) areas, ACA in temporal (31.2±8.2 vs. 27.7±9.7 degrees, P<0.01) and in nasal (30.4±8.5 vs. 27.6±8.6 degrees, P<0.01) areas were seen. ACD, AOD500 and ACA showed significant negative correlation with age (Spearman's correlation coefficient, Rs=-0.38, -0.34, -0.39) and refraction (Rs=-0.36, -0.33, -0.38); and significant positive correlation with axial length (Rs=-0.47, -0.50, -0.47) and the van Herick's grading of peripheral anterior chamber depth (Rs=-0.63, -0.66, -0.67).
Conclusions: :
Using AS-OCT, ACD, AOD500 and ACA could be noninvasively determined in 94.4% of Japanese subjects. Given the same age and refraction, women had narrower anterior chamber than men, and the anterior chamber parameters were correlated with age, refraction, axial length and peripheral anterior chamber depth.
Keywords: anterior chamber • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment