May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Ocular Surface Squamous Neoplasia as the First and Only Apparent Manifestation of Hiv Infection in an Urban Patient Population in Southeast Africa
Author Affiliations & Notes
  • M. S. Spitzer
    Ophthalmology, University Eye Hospital Tuebingen, Tuebingen, Germany
  • T. Chirambo
    Ophthalmology, Lion's Sight First Eye Hospital, College of Medicine, Blantyre, Malawi
  • P. Kayange
    Ophthalmology, Lion's Sight First Eye Hospital, College of Medicine, Blantyre, Malawi
  • E. Yoeruek
    Ophthalmology, University Eye Hospital Tuebingen, Tuebingen, Germany
  • P. Szurman
    Ophthalmology, University Eye Hospital Tuebingen, Tuebingen, Germany
  • K. U. Bartz-Schmidt
    Ophthalmology, University Eye Hospital Tuebingen, Tuebingen, Germany
  • H. N. Batumba
    Ophthalmology, Lion's Sight First Eye Hospital, College of Medicine, Blantyre, Malawi
  • Footnotes
    Commercial Relationships  M.S. Spitzer, None; T. Chirambo, None; P. Kayange, None; E. Yoeruek, None; P. Szurman, None; K.U. Bartz-Schmidt, None; H.N. Batumba, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5127. doi:https://doi.org/
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      M. S. Spitzer, T. Chirambo, P. Kayange, E. Yoeruek, P. Szurman, K. U. Bartz-Schmidt, H. N. Batumba; Ocular Surface Squamous Neoplasia as the First and Only Apparent Manifestation of Hiv Infection in an Urban Patient Population in Southeast Africa. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5127. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the prevalence of undiagnosed and asymptomatic HIV infection in patients with ocular surface squamous neoplasia (OSSN) in an urban patient population in sub-Saharan Africa.

Methods: : A consecutive series of patients presenting with OSSN was evaluated in an African academic center. A detailed history and physical examination in 53 consecutive patients with conjunctival squamous cell carcinoma (SCC) and conjunctival intra-epithelial neoplasia (CIN) was performed. 38 (72%) patients agreed to undergo serological HIV testing

Results: : 79% (30 of 38) of all tested patients were HIV positive. None of the patients had previous HIV testing or was aware of having symptoms of HIV. 70% (n=21) of the HIV positive patients had no other symptoms suggestive of HIV infection or any other disease althoughmany patients recalled that the ocular tumor has been present for more than 6 to 12 months. Patients were far more likely to refuse HIV testing if they were married.

Keywords: AIDS/HIV • tumors • oncology 
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