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I. G. Cox, K. H. Edwards, R. Sun; Comparison of Wavefront Aberrations in Eyes With Implantation of an Aspheric IOL or a Spherical IOL. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5276.
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The objective of this study was to compare wavefront aberration measured in eyes with spherical or aspheric IOLs.
This was a prospective, randomized and multi-center study. A total of 54 subjects received either an aspheric IOL (SofPort AO) or a spherical IOL (AcrySof SA60AT) during cataract surgery from 5 study sites. Wavefront aberration was measured at 3 and 6 months after surgery using the Bausch & Lomb Zywave (I/II) waveFront aberrometer. Prior to data analysis, pupil sizes were standardized at 3mm, 4mm and 5mm. The results were compared statistically between the spherical lens eyes and aspheric lens eyes.
At 3 months postoperatively, mean spherical aberration was 0.02um; 0.07um; 0.18um at 3mm, 4mm and 5mm pupils respectively in the aspheric lens eyes. In the spherical lens eyes, mean spherical aberration was 0.04um; 0.12um; 0.30um at 3mm, 4mm and 5mm pupils respectively. The differences between the aspheric lens eyes and spherical lens eyes were statistically significant at all the pupil sizes (p<0.001). At 6 months postoperatively, mean Spherical Aberration was 0.02um; 0.06um; 0.12um at 3mm, 4mm and 5 mm pupils individually in aspheric lens eyes comparing to 0.04um; 0.11um; 0.28um at 3mm, 4mm and 5mm pupils individually in spherical lens eyes. Again, the differences were statistically significant at all pupil sizes (p<0.001).
The results of this study have confirmed that spherical aberration was significantly reduced in eyes with an aspheric IOL implantation compared to eyes that received a spherical IOL.
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