May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Risk Factors and Clinical Evaluation of Dry Eye Syndrome in Pediatric Population
Author Affiliations & Notes
  • C. Yu
    Ophthalmology, Montefiore Medical Center, New York, New York
  • I. Friedman
    Ophthalmology, Montefiore Medical Center, New York, New York
  • J. Gurland
    Ophthalmology, Montefiore Medical Center, New York, New York
  • Footnotes
    Commercial Relationships  C. Yu, None; I. Friedman, None; J. Gurland, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5322. doi:
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      C. Yu, I. Friedman, J. Gurland; Risk Factors and Clinical Evaluation of Dry Eye Syndrome in Pediatric Population. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5322.

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Abstract

Purpose: : Dry eye syndrome is traditionally thought to be a disease prevalent only in middle-age and elderly populations. However, many children present with symptoms and signs consistent with dry eye syndrome in our pediatric clinic. The purpose of this study is to investigate the prevalence of dry eye syndrome and associated risk factors in the pediatric population.

Methods: : One hundred and sixteen eyes from 58 children(ranging from age 4 to 17) encountered consecutively were studied. Gender, age, ethnicity, past medical history, and presenting symptoms were recorded. Tear break-up time, corneal staining pattern, Schirmer test results, eyelid and conjunctival findings were evaluated.

Results: : Eighteen patients (31%) were found to have symptoms and physical findings consistent with dry eye syndrome. The most frequent symptoms were red eyes and tearing. Among the patients with dry eye syndrome, eight (44%) were males and ten(56%) were females. Past medical history of asthma was significantly more prevalent in patients with dry eye (55%) than the control group (33%) (p-value=0.024). Seasonal allergy was also found to be statistically more prevalent in the dry eye group (61% vs 30%, p-value=0.025).

Conclusions: : Dry eye syndrome was found to be more prevalent in the pediatric population than previously reported. Risk factors such as asthma and seasonal allergy were strongly associated with dry eye syndrome. Immunological and environmental factors may play a major role in the pathogensis of dry eye syndrome in children.

Keywords: cornea: tears/tear film/dry eye • clinical (human) or epidemiologic studies: risk factor assessment • cornea: clinical science 
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