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E. Viso, M. Rodriguez-Ares, F. Gude, R. Touriño; Prevalence of Dry Eye Syndrome in a Spanish Adult Population (the Salnes Eye Study). Invest. Ophthalmol. Vis. Sci. 2008;49(13):5323.
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To describe the prevalence of dry eye syndrome in a general adult population in north-western Spain.
An age-stratified random sample of 1155 subjects older than 40 years was selected in O Salnés area (Spain). From 937 eligible subjects, 654 (69.8%) agreed to participate (mean age (SD): 63.6 (14.4) years, range: 40-96, 37.2% males). A standardised dry eye questionnaire was administered and objective tests were performed. The diagnosis of dry eye was made when one or more of the symptoms of the questionnaire were present often or all the time. Positivity in any dry eye test was also considered indicative of the syndrome. A design based analysis was performed and all calculations were weighted to give unbiased estimates. Agreement between symptoms and signs was analyzed.
Weighted dry eye prevalence was 18.4% (95%CI 15.4-21.3) by symptoms, 37.0% (95%CI 33.2-40.7) by Schirmer test (≤ 5 mm), 15.6% (95%CI 12.7-18.5) by tear film breakup time (≤ 10 s), 13.0% (95%CI 10.3-15.6) by rose bengal staining (≥ 1) and 7.0% (95%CI 4.9-8.9) by fluorescein staining (≥ 1). Women and older subjects were more likely to report symptoms. Agreement between the different diagnostic procedures was poor.
Prevalence of dry eye is high in this adult European population. No agreement is found between signs and symptoms.
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