May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Correlation Between Optical Coherence Tomography and Microperimetry After Surgical Peeling of Idiopathic Epiretinal Membrane
Author Affiliations & Notes
  • A. Nashed
    Ophthalmology, Eye Clinic Saarbrücken, Saarbrücken, Germany
    Ophthalmology, University Eye Clinic Regensburg, Regensburg, Germany
  • P. Saikia
    Ophthalmology, University Eye Clinic Regensburg, Regensburg, Germany
  • H. Helbig
    Ophthalmology, University Eye Clinic Regensburg, Regensburg, Germany
  • J. Hillenkamp
    Ophthalmology, University Eye Clinic Regensburg, Regensburg, Germany
    Ophthalmology, Universtiy Eye Clinic Kiel, Kiel, Germany
  • Footnotes
    Commercial Relationships  A. Nashed, None; P. Saikia, None; H. Helbig, None; J. Hillenkamp, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5363. doi:https://doi.org/
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      A. Nashed, P. Saikia, H. Helbig, J. Hillenkamp; Correlation Between Optical Coherence Tomography and Microperimetry After Surgical Peeling of Idiopathic Epiretinal Membrane. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5363. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare macular sensitivity and macular thickness after surgical peeling of idiopathic epiretinal membrane (IEM) with or without the assistance of Indocyanine green (ICG).

Methods: : 21 eyes of 21 patients who had undergone vitrectomy with removal of IEM were included. 11 patients were operated with the assistance of ICG, 10 patients were operated without ICG. Macular sensitivity and retinal fixation were investigated with the Micro Perimeter 1 (MP-1). Optical coherence tomography (OCT) was used to quantify macular thickness. Best corrected visual acuity (BCVA) was assessed in all patients.

Results: : Macular sensitivity measured with the MP-1 was significantly correlated with macular thickness (r2 0.446, p=0.04). The correlation between macular sensitivity and macular thickness showed similar tendencies whether ICG was used (r2 0.515, p=0.1) or not (r2 0.6, p=0.06). Macular sensitivity (13.18 +/- 3.5 dB), macular thickness (293 +/- 45 µm), and BCVA (0.23 +/- 0.2 logMAR) were without significant difference in patients operated with or without ICG (p=0.65, p=0.47, p=0.97 respectively). Retinal fixation was stable in 8, relatively unstable in 5, and unstable in 8 patients.

Conclusions: : Macular sensitivity correlates negatively with macular thickness after surgical peeling of IEM in eyes operated with or without the assistance of ICG.

Keywords: retina • clinical research methodology • drug toxicity/drug effects 
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