May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Retinal Oxygenation After Laser Photocoagulation in Patients With Proliferative Diabetic Retinopathy
Author Affiliations & Notes
  • S. H. Hardarson
    University of Iceland, Reykjavik, Iceland
    Ophthalmology,
  • R. A. Karlsson
    University of Iceland, Reykjavik, Iceland
    Electrical and Computer Engineering,
  • T. Eysteinsson
    University of Iceland, Reykjavik, Iceland
    Ophthalmology,
  • J. M. Beach
    University of Iceland, Reykjavik, Iceland
    Electrical and Computer Engineering,
  • J. A. Benediktsson
    University of Iceland, Reykjavik, Iceland
    Electrical and Computer Engineering,
  • E. Stefansson
    University of Iceland, Reykjavik, Iceland
    Ophthalmology,
  • Footnotes
    Commercial Relationships  S.H. Hardarson, Oxymap, I; Oxymap, E; Oxymap, P; R.A. Karlsson, Oxymap, I; Oxymap, E; Oxymap, P; T. Eysteinsson, Oxymap, I; Oxymap, P; J.M. Beach, Oxymap, I; Oxymap, E; Oxymap, P; J.A. Benediktsson, Oxymap, I; Oxymap, P; E. Stefansson, Oxymap, I; Oxymap, P.
  • Footnotes
    Support  Eimskip University Fund, Icelandic Research Council, Landspitali Research Fund, University of Iceland Research Fund, Helga Jonsdottir and Sigurlidi Kristjansson Memorial Fund
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5366. doi:https://doi.org/
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    • Get Citation

      S. H. Hardarson, R. A. Karlsson, T. Eysteinsson, J. M. Beach, J. A. Benediktsson, E. Stefansson; Retinal Oxygenation After Laser Photocoagulation in Patients With Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5366. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

Hypoxia in retinal tissue is believed to be a major factor in diabetic retinopathy (DR). Laser treatment may correct retinal hypoxia. The purpose of this study was to measure oxygen saturation in retinal blood vessels in patients with proliferative DR and a history of laser treatment.

 
Methods:
 

The retinal oximeter estimates hemoglobin oxygen saturation in retinal vessels. The oximeter is composed of a fundus camera, beam splitter, light filters and specialized software. Oximetry was performed in 1st and 2nd degree temporal retinal vessels in 20 healthy individuals and 7 patients with proliferative DR. In all 7 patients, DR had been stabilized with laser (PRP). Unpaired t-tests were used for analysis.

 
Results:
 

 

 
Conclusions:
 

Oxygen saturation in both retinal arterioles and venules is higher in patients with proliferative DR and a history of successful laser treatment than in healthy individuals.

 
Keywords: oxygen • diabetic retinopathy • imaging/image analysis: clinical 
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