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S. H. Hardarson, R. A. Karlsson, T. Eysteinsson, J. M. Beach, J. A. Benediktsson, E. Stefansson; Retinal Oxygenation After Laser Photocoagulation in Patients With Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5366.
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Hypoxia in retinal tissue is believed to be a major factor in diabetic retinopathy (DR). Laser treatment may correct retinal hypoxia. The purpose of this study was to measure oxygen saturation in retinal blood vessels in patients with proliferative DR and a history of laser treatment.
The retinal oximeter estimates hemoglobin oxygen saturation in retinal vessels. The oximeter is composed of a fundus camera, beam splitter, light filters and specialized software. Oximetry was performed in 1st and 2nd degree temporal retinal vessels in 20 healthy individuals and 7 patients with proliferative DR. In all 7 patients, DR had been stabilized with laser (PRP). Unpaired t-tests were used for analysis.
Oxygen saturation in both retinal arterioles and venules is higher in patients with proliferative DR and a history of successful laser treatment than in healthy individuals.
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