May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
High-Definition Spectral Domain Optical Coherence Tomography Imaging of the Angle
Author Affiliations & Notes
  • H. Wong
    Dept of Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • M. C. Lim
    Singapore National Eye Centre, Singapore, Singapore
  • L. M. Sakata
    Singapore Eye Research Institute, Singapore, Singapore
  • H. T. Aung
    Singapore Eye Research Institute, Singapore, Singapore
  • D. S. Friedman
    Wilmer Eye Institute and Johns Hopkins Bloomberg School of Public, Singapore, Maryland
  • T. Aung
    Singapore National Eye Centre, Singapore, Singapore
  • Footnotes
    Commercial Relationships  H. Wong, Zeiss, Heidelberg, F; Heidelberg, R; M.C. Lim, None; L.M. Sakata, None; H.T. Aung, None; D.S. Friedman, None; T. Aung, Zeiss, F; Zeiss, C; Zeiss, R.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5434. doi:https://doi.org/
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      H. Wong, M. C. Lim, L. M. Sakata, H. T. Aung, D. S. Friedman, T. Aung; High-Definition Spectral Domain Optical Coherence Tomography Imaging of the Angle. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5434. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To introduce the use of high-definition spectral domain opticalcoherence tomography (HD-SD-OCT) for imaging of the anteriorchamber angle

 
Methods:
 

In this hospital-based prospective case series, 45 phakic subjectsunderwent gonioscopy and HD-SD-OCT (Cirrus, Carl Zeiss Meditec,Dublin, CA). A Volk 60D aspheric lens was mounted over the Cirrusimaging aperture. For angle imaging, the patients’ fixationwas directed outside the instrument, using an external fixationlight, so that iridocorneal angle was centered in the instrument’sfield of view. HD-SD-OCT scans were taken of the temporal andnasal quadrants of each eye.

 
Results:
 

The mean age of the subjects was 62.5 ± 9.1 years andthe majority of subjects were Chinese (91%) and female (62.2%).Cross-sectional HD-SD-OCT allowed in-vivo visualization of thescleral spur in 71/90 (78.9%) quadrants and the terminationof the Descemet’s membrane (Schwalbe’s line) in84/90 (93.3%) quadrants (Left figure). It was possible to imagethe trabecular meshwork in some eyes. Angle closure (Right figure)was observed in 17 eyes with gonioscopy and 12 eyes with HD-SD-OCT(p=0.12, McNemar Test). The two modalities showed good agreement(Kappa = 0.65).

 
Conclusions:
 

HD-SD-OCT can be used for obtaining magnified views of the anteriorchamber angle and has the potential to become a new imagingmodality for angle closure diagnosis.  

 

 
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment • imaging/image analysis: clinical 
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