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H. H. Do, H. K. Kang, P. E. Beaumont; Prognostic Significance of Ophthalmodynamometry in Central Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5438.
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Ophthalmodynamometry can quantify the elevated retinal venouscollapse pressure (VCP) in central retinal vein occlusion (CRVO)as a direct measure of outflow resistance. This study investigateswhether absolute VCP and the ratio of VCP to arterial collapsepressure (ACP) are useful prognostic indicators in CRVO.
The study retrospectively analysed 73 cases of CRVO with centralretinal venous and arterial diastolic pressures measured witha Bailliart type ophthalmodynamometer at initial presentationand during the course of follow-up, at 1 week, 1 month, 3 monthsand 6 months. This was analysed against visual acuity measuredusing a Snellen chart under standardised conditions.
The median VCP decreased 54.0 grams (gm) between the initialand final visit from 105.0gm to 51.0gm. Cases with the VCP greaterthan ACP at initial presentation had a worse visual outcomethan those with a VCP less than or equal to the ACP at 1 week(p=0.012), 1 month (p=0.032), 3 months (p=0.009) and 6 months(p=0.031). An initial high VCP (greater than or equal to 100gm)wasassociated with poor visual acuity throughout the course offollow up. Cases with low (0-49gm) and mid-range (50-99gm) VCPhad variable outcomes.
High initial VCP (greater than or equal to 100gm) and initialVCP greater than the ACP is predictive of worse short term visualoutcome.
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