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M. Yanagihashi, Y. Nakamura, Y. Mitamura, S. Yamamoto; Comparison of Indocyanine Green-Assisted and Triamcinolone Acetonide-Assisted Macular Hole Surgery on Anatomical and Functional Outcomes. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5597. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the anatomical closure and visual outcome after macular hole (MH) surgery with internal limiting membrane (ILM) peeling using indocyanine green (ICG) or triamcinolone acetonide (TA).
Seventy eyes of 68 patients with an idiopathic MH underwent pars plana vitrectomy (PPV) with SF6 gas tamponade between April 2003 to March 2007. Simultaneous phacoemulsification with intraocular lens implantation was performed on 64 eyes. Thirty-three eyes of 32 patients underwent PPV with ILM peeling using ICG (ICG group), and 37 eyes of 36 patients underwent PPV with ILM peeling using TA (TA group). The main outcome measures were anatomical closure and visual acuity before and at 1, 3, and 6 months after surgery.
There was no significant difference between the two groups in the preoperative MH size and visual acuity (P=0.777, P=0.269, respectively). After the primary surgery, the MH was closed in 33 eyes (100%) of the ICG group and 34 eyes (92%) in the TA group (P=0.094). The visual acuity was significantly better in the TA group than in the ICG group at 1 month after surgery (P=0.013). However, there was no significant difference in the visual acuity at 3 and 6 months (P=0.092, P=0.065, respectively).
At the early postoperative period, the visual outcome was better in eyes undergoing TA-assisted PPV than in those undergoing ICG-assisted PPV. However, anatomical results and visual acuity at 3 and 6 months were not significantly different in the two groups.CR: None
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