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D. Gatinel, P. Adam, S. Chaabouni, J. Munck, M. Thévenot, T. Hoang-Xuan, H. Bains, CEROC (Center of Expertise and Research in Optics for Clinicians); Comparison of Corneal and Total Ocular High-Order Optical Aberrations Before and After Myopic Laser in situ Keratomileusis. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5639.
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To evaluate the changes in total and corneal aberrations and the compensation of aberrations within the human eye after conventional myopic laser in situ keratomileusis (LASIK).
Total and corneal aberrations were measured preoperatively and 3 months postoperatively for 57 eyes. The NIDEK EC-5000 excimer laser was used for all treatments. Total and corneal aberrations root-mean-square (RMS) values were calculated out to the 6th Zernike orders for a 6.0-mm pupil diameter. The percentage of increase after surgery was defined by the ratio between the RMS values pre- and postoperatively for each of the corneal and total eye aberration groups. The compensation between corneal and internal aberrations for a given aberration group was defined by the ratio:(corneal aberration group RMS- total eye aberration group RMS)/ corneal aberration group RMS). A p-value less than 0.05 was considered statistically significant.
Postoperatively, higher order aberrations showed a statistically significant increase after myopic LASIK by a factor of 1.77±1.26 (total) and 2.47±2.25 (corneal) (p <0.05). Coma aberration increased by 2.43±2.61 (total) and 2.56±2.66 (corneal) . Spherical aberration increased by a factor 1.46±1.83 (total) and 2.64±2.24 (cornea). The values of the ratio of compensation did not show statistically significant differences before and after LASIK for individual aberrations (p>0.05).
Although myopic LASIK induced significant corneal aberrations, the level of partial compensation of corneal aberrations by internal structures remained unchanged. These results may suggest that a previously described emmetropization that is effective not only with developmental factors but also with acquired variations in corneal shape.
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