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Y. Kim, T. Hwang, D. Choi, D. Wilson; Comparison of Digital Fundus Photographic and Echographic Measurements From Eyes With Choroidal Melanoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5951.
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Accurate assessment of tumor size is critical in treating choroidal melanoma. Echographic measurements are most commonly used, but suffer from intra- and inter-observer variability in measuring tumor maximal linear dimensions (MLD). Digital fundus photographic systems can create a montage that clearly documents the tumor margins. This image can then be used to measure tumor MLD.Few reports compare measurements of tumor MLD by digital fundus photography versus echography. The following study was undertaken to evaluate the potential value of a digital imaging system in measuring the MLD of choroidal melanoma.
We studied 27 eyes in 21 patients recruited between September 2006 and August 2007. Inclusion criteria were: 1) Echographic and digital fundus photographic examination were performed on the same day, and 2) Fundus photography yielded a montage that clearly defined tumor margins.The MLD were measured as follows: for echography, transverse and longitudinal diameters were measured following the Collaborative Ocular Melanoma Study (COMS) standardized echographic protocol, and the larger dimension was selected as the MLD. For fundus photography, the tumor margin was outlined with an electronic pen and the MLD calculated by software (ANKA).
The mean MLD of all tumors recorded were 9.44 mm by echography and 10.50 mm by digital fundus photography. The echographic and photographic measurements of MLD agreed within 1 mm for 13 eyes (48%), 2 mm for 22 eyes (80%) and 3 mm for 25 eyes (93%).Tumor measurements by photography exceeded echographic measurements in 22 eyes (80%). In cases in which the echographic measurement exceeded the photographic measurement, the measurements generally differed by 1 mm.
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