May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Diagnostic and Therapeutic Vitrectomy for Uveitis Management
Author Affiliations & Notes
  • G. F. Graue-Moreno
    Instituto de Oftalmologia Conde de Valenciana, Mexico, Mexico
    Uveitis and Ocular Inmunology,
  • C. Lizana
    Instituto de Oftalmologia Conde de Valenciana, Mexico, Mexico
    Uveitis and Ocular Inmunology,
  • S. Voorduin-Ramos
    Instituto de Oftalmologia Conde de Valenciana, Mexico, Mexico
    Uveitis and Ocular Inmunology,
  • J. Rodriguez
    Instituto de Oftalmologia Conde de Valenciana, Mexico, Mexico
    Retina and Vitreous,
  • M. Pedroza-Seres
    Instituto de Oftalmologia Conde de Valenciana, Mexico, Mexico
    Uveitis and Ocular Inmunology,
  • Footnotes
    Commercial Relationships  G.F. Graue-Moreno, None; C. Lizana, None; S. Voorduin-Ramos, None; J. Rodriguez, None; M. Pedroza-Seres, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 5964. doi:https://doi.org/
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      G. F. Graue-Moreno, C. Lizana, S. Voorduin-Ramos, J. Rodriguez, M. Pedroza-Seres; Diagnostic and Therapeutic Vitrectomy for Uveitis Management. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5964. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To asses the outcome and possible benefits of Pars Plana Vitrectomy (PPV) for diagnostic and therapeutic purposes in patients with uveitis.

Results: : Eighteen patients (22 eyes) from eight men and ten women between 6 and 79 years (standard deviation 21.55 years, average 29.5 years) were included.Previous clinical diagnosis were: Pars planitis (4), Vogt-Koyanagi-Harada syndrome (6 ), ocular toxoplasmosis (2), masquerade syndrome (2), Eales disease (1), ocular syphilis (1), panuveitis in HIV patients (3) and idiopathic panuveitis (3).Seven eyes underwent PPV, 4 eyes PPV plus phacoemulsification, 9 eyes PPV plus lensectomy, 1 eye PPV with lensectomy plus scleral buckling and 1 eye PPV and scleral buckling.Indications for PPV were as follow: uveitic cataract and persistent vitreous opacity(11), uveitic cataract and refractary macular edema(1), rhegmatogenous retinal detachment(4), persistent vitreous hemorrhage (2) and vitreous opacities associated with persistent visual loss (4).PCR was positive for cytomegalovirus in both eyes from a patient with panuveitis associated with HIV (+). Histopathological analysis of vitreous tap in one patient was positive for intraocular lymphoma. Candida albicans was positive in two HIV (+) patients with panuveitis .Patients showed an improvement in visual acuity in 80% of cases after surgery (p<0.05). This improvement was sustained during the follow-up in more than fifty percent of the patients. Complications of PPV were: persistent hypotony (one eye), recurrent retinal detachment (one eye), ocular hypertension and persistent inflammation (1 eye).

Conclusions: : PPV alone or combined with other surgical procedures is effective and safe in controling inflamation in patients with uveitis.

Keywords: vitreoretinal surgery • uveitis-clinical/animal model • inflammation 
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