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N. Kinoshita, F. Toyoda, K. Ishizaki, M. Takezawa, C. Mameuda, H. Yamagami, A. Kakehashi; Surgical Results of First-Time Silicone Oil Tamponade for Neovascular Glaucoma: A New Surgical Method for Neovascular Glaucoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5977.
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To report good surgical results obtained using silicone oil tamponade for neovascular glaucoma.
Thirteen eyes (11 patients) with neovascular glaucoma underwent pars plana lensectomy/pars plana vitrectomy/panretinal photocoagulation including pars plana/silicone oil tamponade (PPL+PPV+EPC+SO tamponade) from 2004 July to 2007 January. Eyes were evaluated for intraocular pressure (IOP), number of antihypertensive eye drops/oral medications, and visual acuity (VA) at the first visit and before and 3 months postoperatively. Nine eyes (8 patients) that then underwent silicone oil removal and intraocular lens (IOL) implantation (SO removal+IOL implantation) also were evaluated similarly 3 months postoperatively.
At the first visit, before, and 3 months after PPL+PPV+EPC+SO tamponade and 3 months after SO removal/IOL implantation, the average IOP values were, respectively, 29±19, 23±12, 13±5, and 17±10 mmHg; the average numbers of antihypertensive eye drops/oral medications were 0.7±1.4, 2.1±2.0, 0.6±0.7, and 1.2±1.2 tablets; and the average VA values were 0.11, 0.05, 0.03, and 0.04.
Good outcomes were achieved due to vitrectomy and panretinal photocoagulation to the pars plana by PPL+PPV and because migration of vascular endothelial growth factor and inflammatory cytokines to the anterior chamber that generally occurs postoperatively was prevented by preservation of the anterior capsule and SO tamponade. SO tamponade combined with PPL+PPV+EPC can decrease IOP significantly in patients with neovascular glaucoma.
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