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J. K. Chen, R. N. Khurana, Q. Nguyen, D. V. Do; The Incidence of Endophthalmitis Following Transconjunctival Sutureless 25-Gauge Vitrectomy Compared to 20-Gauge Vitrectomy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):5979.
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To determine the incidence of endophthalmitis following 25-gauge and standard 20-gauge vitrectomy.
The event rates of post-operative endophthalmitis were 0.03 % (1/3046) after 20-gauge vitrectomy and 0.2 % (1/431) after 25-gauge vitrectomy (P = 0.23). In the endophthalmitis case that occurred after 25-gauge vitrectomy, a combined phacoemulsification cataract surgery was performed with the 25-gauge vitrectomy. Analyses of event rates of post-operative endophthalmitis after combination of phacoemulsification cataract surgery and vitrectomy were 0 % (0/170) for 20-gauge vitrectomy and 0.02 % (1/46) for 25-gauge surgery vitrectomy (P = 0.21).
There was an increased risk of post-operative endophthalmitis following 25-gauge vitrectomy in comparison to 20-gauge surgery; however, this difference was not statistically significant given the low number of measured outcomes.
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