May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Long-Term Evaluation for Mitomycin C Subconjuntival Injection as Adjunctive Therapy Before Pterygium Excision
Author Affiliations & Notes
  • R. F. dos Reis
    Ophthalmology, CLIHON - Ophthalmological Center, Feira de Santana, Brazil
  • H. L. de Oliveira Neto
    Ophthalmology, UEFS - University of Feira de Santana / CLIHON - Ophthalmological Center, Feira de Santana, Brazil
  • J. Silva
    Ophthalmology, CLIHON - Ophthalmological Center, Feira de Santana, Brazil
  • J. Campelo
    Ophthalmology, CLIHON - Ophthalmological Center, Feira de Santana, Brazil
  • Footnotes
    Commercial Relationships  R.F. dos Reis, None; H.L. de Oliveira Neto, None; J. Silva, None; J. Campelo, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 6028. doi:https://doi.org/
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      R. F. dos Reis, H. L. de Oliveira Neto, J. Silva, J. Campelo; Long-Term Evaluation for Mitomycin C Subconjuntival Injection as Adjunctive Therapy Before Pterygium Excision. Invest. Ophthalmol. Vis. Sci. 2008;49(13):6028. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To evaluate the safety and recurrence rates using 0.1ml of 0.15mg/ml Mitomycin C subconjuntival injection as adjunctive therapy 1 month before Pterygium surgery in a long-term analysis.

 
Methods:
 

Eleven patients ( 4 male, 7 female; eleven eyes. Ages ranging from 39 to 72; average 54.55 years old ) with pterygium were enrolled.

 
Results:
 

During an average follow-up period of 38.54 months there was no recurrences (defined as fibrovascular growth > 1mm past the limbus). No patients presented visual decrease. Two patients (18.18%) presented considerable scleral thinning at the injection site, one with posterior fibrovascular tissue growth on this area. Three patients (27.27%) complained monocular mild pain and photophobia, since the subconjuntival injection, persisting until last evaluation.

 
Conclusions:
 

The use of Mitomycin C subconjuntival injection 1 month before pterygium extraction was effective against recurrence in our case series (without recurrences) .It is a very simple and fast surgycal technique to perform, but we must take caution against the potential side effects for Mitomycin C use. We could observe scleral thinning with the 0.15mg/ml dose (2/11) and patients complaining ocular pain and photophobia years after the injection (3/11).  

 
Keywords: pterygium • conjunctiva • anterior segment 
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