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R. Iranmanesh, E. Shrier, J. Zheutlin, L. Yannuzzi; Fundus Autofluorescence in Acute Exudative Polymorphous Vitelliform Maculopathy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):122. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the fundus autofluorescence (AF) findings in patients with acute exudative polymorphous vitelliform maculopathy (AEPVM).
Three patients with AEPVM were imaged with fundus AF photography using a fundus based camera system. Complete clinical examination also included fundus photography, FA, OCT and genetic testing.
The three patients all had bilateral, central, symmetric, subretinal vitelliform lesions. Fundus AF photography demonstrated that the material was intensely hyperautofluorescent, consistent with the presence of lipofuscin.
In these patient with AEPVM, fundus AF imaging supports the theory that lipofuscin accumulates in this rare disorder and suggests that cell loss may occur despite recovery of near-normal vision in all reported cases. To our knowledge, this is the first description of fundus AF imaging in patients with AEPVM.
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