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J. S. Kroisamer, C. Simader, S. Michels, U. Schmidt-Erfurth; Evaluation of Microperimetric Findings in Normal Individuals: Influence of Room Light Intensity. Invest. Ophthalmol. Vis. Sci. 2007;48(13):152. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
Automated static threshold microperimetry has been established in clinical practice to evaluate the macular function, the progress of diseases and the effects of therapy. The aim of this comperative study was to evaluate, if microperimetric findings are affected by room light intensity.
Static threshold perimetry was performed twice a day using the MP1 microperimeter (Nidek-Technologies, Softwareversion 1.4.2) in 35 dilated eyes of volunteers without any history of ocular diseases, other than ametropia. The chosen room light intensities were 0.16-0.25 lux (dark) and 3-4.5 lux (bright). The examination setting did not vary, a standardized grid with 25 stimuli and a 1° red circle fixation point was used. The sequence of examination was randomized to avoid bias by learning effects. The microperimetric findings were analysed by SPSS for Windows 11.5. The study followed the tents of the Declaration of Helsinki and was approved by the ethics committee of the Medical University of Vienna.
The mean total light treshold of all 25 locations was 382.3 ± 22.1 dB in a brightly illuminated room and 391 ± 22.3 dB in a dark room. The examinations in bright rooms showed higher mean threshold value than examinations in the dark. The mean difference between both examinations was 8.7 ± 16.1 dB. Linear regression analysis of the microperimetric results showed a significant correlation (p< 0,05).
The results indicate that macular function evaluation using the Nidek MP1 system are effected significantly by room light intensity. Therefore a constant, standardized room illumination is recommended in order to obtain comparable results.
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