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C. Serny, F. Mura, O. Rebollo, B. Arnaud, C. Arndt; Hemodilution With and Without Triamcinolone at the Initial Phase of Vein Occlusion: A Retrospective Comparative Study. Invest. Ophthalmol. Vis. Sci. 2007;48(13):298.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the effectiveness of intravitreal triamcinolone acetonide in the treatment of macular edema due to central retinal vein occlusion in patients treated with hemodilution.
In this study, 30 eyes of 30 patients presenting with a central vein occlusion were analyzed retrospectively. All were treated with isovolemic hemodilution (hemodilution group) and 10 patients received additional intravitreal triamcinolone (triamcinolone group). Examination included measurement of best-corrected visual acuity (BCVA) for distance, measurement of intraocular pressure, fluorescein angiography, foveal retinal thickness measurement by optical coherence tomography.
On inclusion, there was no significant difference between the two groups in terms of age, risk factors and visual function. BCVA significantly improved in both groups at 1 month and 3 months, the improvement was significantly greater in the group of patients treated with triamcinolone and hemodilution compared with the group of patients treated with hemodilution alone. The macular thickness significantly improved at 1 and 3 months in the triamcinolone group whereas it remained unchanged in the hemodilution group.
An intravitreal injection of triamcinolone appears to increase the benefit of isovolemic hemodilution.
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