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J. M. Sturm, D. B. Lyon, K. B. Desai; Corneal Ulcer Associated With Parry-Romberg Syndrome. Invest. Ophthalmol. Vis. Sci. 2007;48(13):358.
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To report two cases of neurotrophic corneal ulcer associated with progressive facial hemiatrophy (Parry-Romberg syndrome).
In two patients, corneal ulcers developed in association with ipsilateral facial atrophy, primarily of the cheek and jaw. After extended antibiotic therapy, the corneal ulcers were determined to be of neurotrophic origin. One patient had penetrating keratoplasty as a final treatment and the other patient had a full thickness conjunctival flap.
Neurotrophic corneal ulcerations are a rare and potentially devastating manifestation of Parry-Romberg syndrome.
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