Adenovirus Conjunctivitis Diagnosis Using RPS Adenodetector®

Abstract

Purpose:: To evaluate the RPS Adenodetector^®, a rapid immunochromatographic test, in the diagnosis of patients with clinical overt adenoviral conjunctivitis

Methods:: Consecutive case series. Patients underwent conjunctiva scraping for RPS Adenodetector^® test and culture to identify adenovirus

Results:: A total of 11 patients were studied, and 10 had unilateral disease. Five (45,5%) had symptoms for 2 days, 5 for three days, and 1 for 7 days. Adenovirus culture was positive in 8 patients (73%) and RPS Adenodetector^® was positive in 9 (82%) patients. Eight patients had adenovirus identification by both methods. In one patient the RPS Adenodetector^® was positive in contrast with a negative culture. All two patients revealing negative RPS Adenodetector^® results also had negative cultures. The sensitivity was 100% and the specificity was 67%

Conclusions:: The RPS Adenodetector^® is a useful tool in rapid diagnosis of adenovirus conjunctivitis and may contribute in the spread control of this highly contagious disease

Clinical Trial:: Own University

Keywords: conjunctivitis • adenovirus • detection