May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Investigation of Frequency Specificity of Ocular Effects Through Quasi-Millimeter and Millimeter Wave Exposure
Author Affiliations & Notes
  • M. Kojima
    Kanazawa Medical University, Kahoku, Japan
    Depatment of Ophthalmology,
  • Y. Yamashiro
    Kanazawa Medical University, Kahoku, Japan
    Division of Vision Research for Environmental Health, Medical Research Institute,
  • M. Hanazawa
    National Institute of Information and Communications Technology, Koganei, Japan
  • S. Watanabe
    National Institute of Information and Communications Technology, Koganei, Japan
  • H. Sasaki
    Kanazawa Medical University, Kahoku, Japan
    Depatment of Ophthalmology,
  • M. Taki
    Department of Electrical Engineering Graduate School of Engineering, Tokyo Metropolitan University, Hachioji, Japan
  • K. Sasaki
    Kanazawa Medical University, Kahoku, Japan
    Division of Vision Research for Environmental Health, Medical Research Institute,
  • Footnotes
    Commercial Relationships M. Kojima, None; Y. Yamashiro, None; M. Hanazawa, None; S. Watanabe, None; H. Sasaki, None; M. Taki, None; K. Sasaki, None.
  • Footnotes
    Support *This study was supported by a safety guideline study of the Ministry of Internal Affairs and Communications of Japan.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 395. doi:
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      M. Kojima, Y. Yamashiro, M. Hanazawa, S. Watanabe, H. Sasaki, M. Taki, K. Sasaki; Investigation of Frequency Specificity of Ocular Effects Through Quasi-Millimeter and Millimeter Wave Exposure. Invest. Ophthalmol. Vis. Sci. 2007;48(13):395.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: The validity of limit exposure guidelines of 3-300 GHz (10 mW/cm2) for a quasi-millimeter and a millimeter wave was examined with ocular temperature changes during exposure and ocular injury after exposure.

Methods:: Pigmented rabbits were exposed unilaterally to an 18, 22, 26.5 GHz or 26.5, 35, 40 GHz quasi- and millimeter-wave with lens antenna for 3 minutes. The same average incident power for each frequency was exposed to the center of the rabbit cornea. Both forward and reverse powers were monitored with a power meter. Ocular temperature changes (cornea, lens, vitreous, retrobulbar) during a 3 min. exposure were measured with a Fluoroptic thermometer and corneal surface temperature was measured with a thermometer. For evaluating ocular injury, a rabbit was exposed to one frequency (18, 22, 26.5, 35, 40 GHz) with 800 mW/cm2 for 6 min. Ocular changes were evaluated by slit lamp and ocular inflammation was measured by laser flare meter immediately after and 1 day after exposure.

Results:: Cornea and lens temperature rise were detected by exposure with all examined frequencies. The highest ocular and corneal surface temperature was 40 GHz, followed by 35, 22 and 18 (almost the same), and the lowest was 26.5 GHz. Ocular injury by 800 mW/cm2 for 6 min. exposure was seen only with 40 GHz. Miosis and iris vasodilation were seen immediately after exposure, and corneal epithelial defect at the center of the cornea and corneal opacity were seen one day after exposure.

Conclusions:: It was suggested that thermal and biological reactions differed according to frequency, even when the average incident power was the same.

Keywords: radiation damage: light/UV • cornea: epithelium • inflammation 
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