May 2007
Volume 48, Issue 13
ARVO Annual Meeting Abstract  |   May 2007
Poor Contrast Sensitivity Predicts Subsequent Visual Acuity Loss in Patients Referred for Vision Rehabilitation
Author Affiliations & Notes
  • M. Jackson
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard, Boston, Massachusetts
    Ophthalmology, VIHA, Victoria, British Columbia, Canada
  • K. Bassett
    Ophthalmology, University of British Columbia, Vancouver, British Columbia, Canada
  • E. Sayre
    Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, British Columbia, Canada
  • Footnotes
    Commercial Relationships M. Jackson, None; K. Bassett, None; E. Sayre, None.
  • Footnotes
    Support CNIB E.A. Baker Applied Research Grant
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1163. doi:
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    • Get Citation

      M. Jackson, K. Bassett, E. Sayre; Poor Contrast Sensitivity Predicts Subsequent Visual Acuity Loss in Patients Referred for Vision Rehabilitation. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1163.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose:: To determine the association between measured contrast sensitivity at baseline and change in measured acuity between baseline and one year follow-up in patients referred for vision rehabilitation.

Methods:: 225 patients were enrolled in a one year prospective cohort study. Measured parameters included age, gender, acuity, contrast sensitivity, falls, hallucinations, depression, independence and time-trade.

Results:: After one year 19 were deceased, 54 were lost to follow-up and 152 patients were seen in follow-up. At baseline 33% of patients had > 6/18 acuity, no patients had > log 1.65 contrast sensitivity measured with Pelli-Robson chart and 52% had measured contrast sensitivity better than log 0.75. Considering log contrast sensitivity as a dichotomous variable (better than 0.75) measured contrast sensitivity at baseline was a significant predictor of subsequent change in visual acuity at one year. Odds ratio was 0.349 (95% confidence interval 0.144, 0.849) adjusting for baseline visual acuity (by quartiles), gender, age, falls, depression and hallucinations.

Conclusions:: Poor contrast sensitivity is a significant predictor of subsequent loss of acuity in patients undergoing vision rehabilitation.

Keywords: contrast sensitivity • low vision • visual acuity 

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