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B. Baumann, E. Götzinger, M. Pircher, C. K. Hitzenberger; Imaging of External Ocular Tissue With Spectral Domain Polarization Sensitive Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1183.
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© ARVO (1962-2015); The Authors (2016-present)
To demonstrate the ability of spectral domain polarization sensitive optical coherence tomography (OCT) system to record reflectivity and birefringence images of external human ocular tissue in vivo.
A novel spectral domain polarization sensitive OCT system was constructed. A super luminescent diode with a center wavelength of 840 nm and a bandwidth of 50 nm was used to illuminate the sample tissue. The new system requires only a single spectrometer CCD camera to record the polarization sensitive spectral domain data. Compared to previous systems, this reduces system complexity and costs. With a rate of 20000 A-lines/s, the tissue parameters on reflectivity, retardation, and optic axis orientation were recorded simultaneously. Polarization sensitive OCT images of external ocular tissue were recorded in the eyes of healthy volunteers.
Different structures can be identified based on their polarizing properties: the conjunctiva is non-birefringent, the sclera shows moderate birefringence of varying axis orientation. In addition, a highly birefringent layer, probably tendon of the musculus rectus medialis, can be distinguished.
The use of polarization sensitive OCT reveals details on the polarization properties of the imaged ocular tissue, allowing to differentiate structures that are difficult to distinguish in intensity based images. The benefits of a spectral domain system are the high sensitivity and image acquisition speed.
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