May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Doppler Optical Coherence Angiography for Retinal Vessels
Author Affiliations & Notes
  • S. Makita
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
  • M. Miura
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
    Department of Ophthalmology, Tokyo Medical University, Ami, Japan
  • Y. Hong
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
    Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea
  • M. Yamanari
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
  • T. Yatagai
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
  • Y. Yasuno
    Computational Optics Group, University of Tsukuba, Tsukuba, Japan
  • Footnotes
    Commercial Relationships S. Makita, None; M. Miura, None; Y. Hong, None; M. Yamanari, None; T. Yatagai, None; Y. Yasuno, None.
  • Footnotes
    Support JST Grant, JSPS Grant 15760026, 18360029, 18•3827
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1197. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      S. Makita, M. Miura, Y. Hong, M. Yamanari, T. Yatagai, Y. Yasuno; Doppler Optical Coherence Angiography for Retinal Vessels. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1197. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose:: To observe the three-dimensional retinal vasculature and segment the retinal vessels with Doppler optical coherence angiography

Methods:: Three-dimensional high-speed spectral domain OCT imaging is applied for the in vivo human eye. This system operates at 27,000 A-scan/s and acquires a three-dimensional volume set consisting of 1024 x 140 A-scans within 5.5 seconds. This volume set is processed by Doppler analysis for three-dimensional blood vessel imaging. For contrast enhancement and segmentation of the retinal vessels, two-dimensional line filtering based on the Hessian matrix is applied for en-face vessel images, and then, the line filter is applied for cross-sections of flow images, which is parallel to the blood vessels. Healthy normal volunteers are examined.

Results:: The contrast enhanced three-dimensional blood flow images reveal the retinal vessel structures. And the distribution of the retinal vessel angles is obtained by the line filtering

Conclusions:: Doppler OCA enables the measurements of three-dimensional retinal vessel structure. The contrast enhancement and vessel angle measurement based on two-dimensional line filtering is rather realistic than three-dimensional filtering for large OCT volume set. The vessel angle measurement is one of the step toward absolute blood flow measurement.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • image processing • retina 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×