May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Re-Invented Nasolacrimal System Among Selected Subungulate Species
Author Affiliations & Notes
  • D. A. Samuelson
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • G. Reppas
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • M. Wong
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • P. A. Lewis
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • K. P. Barrie
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • A. R. Graham
    Small Animal Clinical Sciences, University of Florida, Gainesville, Florida
  • Footnotes
    Commercial Relationships D.A. Samuelson, None; G. Reppas, None; M. Wong, None; P.A. Lewis, None; K.P. Barrie, None; A.R. Graham, None.
  • Footnotes
    Support CVM Seed Grant, Florida Fish and Wildlife Grant
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1214. doi:
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      D. A. Samuelson, G. Reppas, M. Wong, P. A. Lewis, K. P. Barrie, A. R. Graham; Re-Invented Nasolacrimal System Among Selected Subungulate Species. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1214.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: Members representing the three subungulate orders, Hyracoidea, Proboscidea, and Sirenia, possess nasolacrimal systems not usually encountered among mammalian species. We have discovered that the Asian elephant (Elephas maximus), the rock hyrax (Procavia capensis), and the West Indian manatee (Trichecus manatus) lack both lacrimal glands, lacrimal punctae, and nasolacrimal ducts and that the nasolacrimal systems of these species have been little understood. To that end, we have examined anatomically the nasolacrimal systems associated with their eyes.

Methods:: Freshly collected formalin-preserved specimens from anterior adnexa of two or more individuals of the Asian elephant, rock hyrax, and West Indian manatee were examined stereomicroscopically and medial, central and lateral portions of each upper and lower palpebrae, as well as entire nictitating membranes (tertia palpebrae) and associated glandular tissue were embedded, sectioned and treated with a variety of stains that included: H&E, Masson's trichrome, and PAS.

Results:: In addition to the absence of lacrimal glands, there was a lack of tarsal (Meibomian) glands in either upper or lower eyelid of each species. However, the Asian elephant possessed highly developed sebaceous glands associated with each palpebral cilium (lash) and neighboring hair. The hyrax possessed uniquely developed sebum-forming glands within the anterior margin of the nictitating membrane. The eyelids of both the manatee and elephant contained extensive accessory glands, having been largely mucous in the manatee and serous in the elephant. All spp had well developed tubuloalveolar glands of the nictitating membrane, which were mostly mucous in the manatee, serous in the elephant and seromucous in the hyrax.

Conclusions:: The three orders that the present spp represent are believed to be ancestrally linked through skeletal and dental evidence. The lack of traditional nasolacrimal systems in these animals support their common evolutionary origin. The loss of both lacrimal and tarsal glands as well as those components for tear drainage suggest a shared aquatic past. The different ways that sebum-forming glands were reformed so that an oily layer is able to cover the seromucous portion of tears of the Asian elephant and the rock hyrax most likely are the result of the different ecological pressures encountered during their subsequent evolution.

Keywords: comparative anatomy • eyelid • lacrimal gland 
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