May 2007
Volume 48, Issue 13
ARVO Annual Meeting Abstract  |   May 2007
Corneal Abnormalities in Congenital Aniridia Evaluated With Pachymetry and Anterior Segment Imaging
Author Affiliations & Notes
  • D. Bremond-Gignac
    Ophthalmology, Robert Debre Hospital, APHP, Paris, France
    INSERM U598, Paris, France
  • H. Copin
    Histology Embryology Cytogenetics, CHU, Amiens, France
  • Footnotes
    Commercial Relationships D. Bremond-Gignac, None; H. Copin, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1216. doi:
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      D. Bremond-Gignac, H. Copin; Corneal Abnormalities in Congenital Aniridia Evaluated With Pachymetry and Anterior Segment Imaging. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1216. doi:

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose:: to evaluate the mean corneal central thickness and anterior segment analysis with Scheimpflug imaging of congenital aniridia patients

Methods:: Ten congenital aniridia patients were evaluated for corneal central thickness with a contact pachymeter (Nidek) and three were also analysed with Pentacam. Corneal topography, anterior chamber depth, non contact pachymetry and Scheimplflug imaging. Patient range was from 3 to 25 years-old. Younger patients were evaluated under anesthesia during general examination for aniridia.

Results:: Central corneal thickness was markedly and significantly higher than in general population range from 560µ to 800µ and these values were significantly and markedly higher than in general population. Anterior chamber depth was evaluated from 2.26 mm to 2.74 mm. Scheimpflug imaging appreciated lens zonula.

Conclusions:: Congenital aniridia is a panocular disease with developmental abnormalities, limbal stem cell deficiency and trabeculum dysgenesia. Glaucoma is a complication of aniridic eye and an evaluation of corneal thickness allow to estimate the precise ocular pressure.

Keywords: anatomy • anterior segment • imaging/image analysis: clinical 

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