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K. Hirooka, III, M. Takagishi, T. Baba, H. Takenaka, F. Shiraga; Optical Coherence Tomography Study of Filtering Blebs After Trabeculectomy With a Fornix Based Conjunctival Flap. Invest. Ophthalmol. Vis. Sci. 2007;48(13):868.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the relation between filtering bleb function and optical coherence tomography (OCT), and to establish a new classification of filtering blebs on the basis of OCT findings.
One year observational case series. Seventy-one eyes of 64 consecutive patients who underwent primary trabeculectomy with mitomycin C (MMC) and a fornix based conjunctival flap. Filtering blebs were examined by using OCT. The surgical success was defined by the following criteria: (A) intraocular pressure (IOP) ≤ 18 mmHg and IOP reduction ≥ 20%; and (B) IOP ≤ 15 mmHg and IOP reduction ≥ 25%. Success rates among classified groups were compared using Kaplan-Meier survival curves and the log-rank test.
Blebs were classified into three different categories on the basis of the following OCT patterns; diffuse type (30 eyes), layer type (24 eyes) and space type (17 eyes). For criteria A, success rates were 97%, 79%, and 94% (P = 0.07) in diffuse type bleb, layer type bleb, and space type bleb, respectively; while the success rates for criteria B, 97%, 75%, and 94% (P = 0.03) in these type blebs, respectively.
In trabeculectomy with MMC and a fornix based conjunctival flap, postoperative OCT findings of filtering blebs are significantly associated with success rates when lower IOPs are required.
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