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F. Mazzolani, L. de Polo, G. Taibbi, C. Cattalini, H. Spinnler, N. Orzalesi; Comparison of HRT II and HRT III Optic Disc Analysis in Patients Affected by Multiple Sclerosis. Invest. Ophthalmol. Vis. Sci. 2007;48(13):914.
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To compare HRT III and HRT II (Heidelberg Engineering GmbH, Dossenheim, Germany) in detecting subclinical changes of optic disc in patients suffering from multiple sclerosis (MS).
Twenty eyes of 10 patients suffering from clinical MS under medical treatment and twenty eyes of 10 normal patients were analyzed . All the patients underwent a complete clinical examination and those with history of optic neuritis or visual disturbances of all kind were excluded. A tomography of the optic disc with HRT III and HRT III was made by the same operator in the same day. The following stereometric parameters were analyzed: Rim Volume, Linear Cup/Disk Ratio, Mean RNFL Thickness, Moorfields classification and Glaucoma Probability Score (GPS).
showed values within normal range for all the stereometric parameters except the GPS score which was outside normal limits in 12% of patients affected by multiple sclerosis. HRT II showed values within normal range for al the stereometric parameters in normals and MS patients. The agreement between the two tomographs was good for Rim Volume and Mean RNFL Tickness (t Test, 0,2>p>0,1), less for Linear Cup/Disk Ratio (t Test, p=0.5).
HRT III and HRT II did not detect any difference in optic disc parameters between normal subjects and MS patients with no ocular involvment.
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