May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Corneal Hysteresis Is Associated With Severity of Visual Field Damage in Glaucoma Patients
Author Affiliations & Notes
  • P. Pillai
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • J. A. Ackerman
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • J. Schiffman
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • W. Feuer
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • S. J. Gedde
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • R. K. Parrish II
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • R. K. Lee
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • Footnotes
    Commercial Relationships P. Pillai, Reichert, F; J.A. Ackerman, Reichert, F; J. Schiffman, None; W. Feuer, None; S.J. Gedde, None; R.K. Parrish II, Reichert, F; R.K. Lee, Reichert, F.
  • Footnotes
    Support Supported by NIH center grant P30 EY01480, EY016775 (to RKL), and by an unrestricted grant to the University of Miami from Research to Prevent Blindness.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1242. doi:https://doi.org/
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    • Get Citation

      P. Pillai, J. A. Ackerman, J. Schiffman, W. Feuer, S. J. Gedde, R. K. Parrish II, R. K. Lee; Corneal Hysteresis Is Associated With Severity of Visual Field Damage in Glaucoma Patients. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1242. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To determine the correlation between corneal hysteresis (CH) and severity of visual field loss in patients with primary open angle glaucoma.

Methods:: The Ocular Response Analyzer (ORA; Reichert, Buffalo, NY) was used to measure corneal hysteresis in patients with primary open angle glaucoma. ORA waveforms and patient clinical history were reviewed with a glaucoma specialist for appropriate glaucoma diagnosis and ORA data integrity. CH values were compared to mean deviation and pattern standard deviation on Humphrey visual fields performed within one year of CH measurements.

Results:: In POAG patients (n=107), a statistically significant correlation between CH and visual field parameters was observed. A small but significant correlation was observed between CH and mean deviation (r= 0.3, p <0.001) and pattern standard deviation (r= 0.2, p = 0.002) on Humphrey visual fields in POAG eyes. No significant difference in CH between right and left eyes of POAG patients was observed.

Conclusions:: Corneal hysteresis has a small to moderate correlation with visual field severity in eyes with primary open angle glaucoma. POAG eyes with more severe glaucoma damage based upon visual fields tended to have higher corneal hysteresis. Hysteresis is a biomechanical property of the cornea that may be a surrogate marker for patients with increased risk for glaucomatous visual field loss.

Keywords: visual fields • clinical (human) or epidemiologic studies: risk factor assessment • cornea: clinical science 
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