May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Effects of Trabeculectomy With Mitomycin C on 24-Hour Intraocular Pressure of Contralateral Eyes
Author Affiliations & Notes
  • Y. Nomura
    Department of Ophthalmology and Visual Sciences Osaka City University of Medicine, Osaka, Japan
  • S. Ataka
    Department of Ophthalmology and Visual Sciences Osaka City University of Medicine, Osaka, Japan
  • S. Nakakura
    Department of Ophthalmology and Visual Sciences Osaka City University of Medicine, Osaka, Japan
  • K. Kurita
    Department of Ophthalmology and Visual Sciences Osaka City University of Medicine, Osaka, Japan
  • K. Shiraki
    Department of Ophthalmology and Visual Sciences Osaka City University of Medicine, Osaka, Japan
  • Footnotes
    Commercial Relationships Y. Nomura, None; S. Ataka, None; S. Nakakura, None; K. Kurita, None; K. Shiraki, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1263. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Y. Nomura, S. Ataka, S. Nakakura, K. Kurita, K. Shiraki; Effects of Trabeculectomy With Mitomycin C on 24-Hour Intraocular Pressure of Contralateral Eyes. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1263. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose:: To examine the effects of trabeculectomy with mitomycin C (MMC) on the intraocular pressure (IOP) of contralateral eyes.

Methods:: Among the patients who had surgery from 2005 till 2006, unilaterally-treated eight patients (5 males and 3 females) who had successful course with post-operative IOP at office (office IOP) (<13mmHg) and whose pre- and post- operative 24-hour IOP could be measured were reviewed retrospectively. The mean patient age was 61.5 years old (range, 21-82 years old). Three patients had normal tension glaucoma, and five patients had primary open angle glaucoma. The pre-operative medication of anti-glaucomatous drugs on the contralateral eyes was continued in all patients. The pre- and 6 months post-operative mean office IOPs were both the average of the IOPs on three consecutive visits. The 24-hour IOPs were measured with a Goldmann applanation tonometer at 3-hour intervals in the sitting position preoperatively and 6 months after the surgery.

Results:: In the operated eyes, the mean office IOP, the mean 24-hour IOP, and the 24-hour IOP fluctuation decreased significantly from 16.75 ± 6.45 mmHg to 10.13 ± 2.85 mmHg (p<0.05), from 18.86 ± 5.35 mmHg to 9.67 ± 2.38 mmHg (p<0.01), from 9.50 ± 3.25 to 3.25 ± 1.58 mmHg (p<0.01), respectively. In the contralateral eyes, the mean office IOP and the mean 24-hour IOP showed no statistically significant differences with 15.63 ± 3.66 mmHg preoperatively and 14.63±3.11 postoperatively (p=0.57), and similarly 16.71 ± 3.23 mmHg and 15.43 ± 3.23 mmHg (p=0.44), respectively. However, the 24-hour IOP fluctuation decreased significantly from 9.00 ± 3.25 mmHg to 5.00 ± 1.51 (p <0.01).

Conclusions:: Trabeculectomy with MMC may reduce the diurnal fluctuation of IOP in contralateral eyes.

Keywords: intraocular pressure • clinical (human) or epidemiologic studies: outcomes/complications 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×