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S. Pilli, D. Mathapati, J. Jarzabek, V. Felcida, G. Menon; Optical Coherence Tomography Findings in Patients Undergoing Re-Treatment With Photodynamic Therapy for Classic Sub-Foveal Choroidal Neovascularization. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1449. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the retinal morphology by optical coherence tomography (OCT) in patients undergoing re-treatment with photodynamic therapy (PDT) and assess its correlation with fluorescein angiography (FA) at 3 monthly follow-ups.
34 eyes were analysed, the decision to re-treat was based on evidence of leakage on FA and had undergone OCT prior to re-treatment with PDT. The OCT patterns were classified into: inner retinal cystoid spaces; diffuse intra-retina fluid; subretinal fluid and a combination of subretinal fluid iwth intra-retinal fluid.
The presence of inner retinal cystoid spaces was seen in 15 eyes (44.11%), diffuse intraretinal fluid was noted in10 eyes (29.41%) and combination of intra-retinal and sub-retinal fluid was seen in 9 eyes (26.47%). No eyes with subretinal fluid only required treatment.
The persistence of leakage seen on FA at 3 monthly follow-ups corresponded mostly with presence of intra-retinal fluid, predominantly as inner cystoid spaces by OCT indicating the need for re-treatment.
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