May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Posterior Sub-Tenon Triamcinolone Injection for Macular Edema Associated With Retinal Vein Occlusion
Author Affiliations & Notes
  • V. H. Tran
    Retina, Jules Gonin Eye Hospital, Lausanne Vaud, Switzerland
  • A. Ambresin
    Retina, Jules Gonin Eye Hospital, Lausanne Vaud, Switzerland
  • T. J. Wolfensberger
    Retina, Jules Gonin Eye Hospital, Lausanne Vaud, Switzerland
  • Footnotes
    Commercial Relationships V.H. Tran, None; A. Ambresin, None; T.J. Wolfensberger, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1548. doi:https://doi.org/
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      V. H. Tran, A. Ambresin, T. J. Wolfensberger; Posterior Sub-Tenon Triamcinolone Injection for Macular Edema Associated With Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1548. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate the effectiveness and safety of posterior sub-Tenon retrobulbar triamcinolone injection for macular edema associated with central (CRVO) or branch retinal vein occlusion (BRVO).

Methods:: In a prospective interventional case series manner, the study included 17 eyes of 17 patients characterized by macular edema lasting more than 3 months. Nine eyes presented with CRVO, 8 eyes with BRVO. One patient with CRVO and 1 with BRVO had undergone previous vitrectomy associated with intravitreal triamcinolone. Posterior sub-Tenon injection of 40 mg triamcinolone was performed in topical anesthesia, and visual and anatomic responses were evaluated.

Results:: Mean foveal thickness was 535.9 ± 113.8 µm preoperatively, 344.2 ± 155.9 µm at 1 month follow-up, 306.3 ± 142.7 µm at 3 month follow-up and 278.3 ± 133.0 µm at 6 month follow-up. Statistical analysis showed significant differences between preoperative and postoperative measurements (P < .0001, at 1 and 6 months, paired t test). Improvement of visual acuity by at least 0.2 logMAR (logarithm of the minimum angle of resolution) was seen in 12 (70%) of the 17 eyes. Patients who had undergone vitrectomy previously had a better response on foveal thickness; however the visual acuity did not improved more than the overall treated patients. Intraocular pressure elevation of 22 mmHg or higher was found in 5 (29%) of 17 eyes and controlled with antiglaucoma medication in all cases. Cataract progression was noted in 4 of 14 phakic eyes.

Conclusions:: Posterior sub-Tenon injection of triamcinolone appears to be an effective treatment for long-standing macular edema associated with CRVO or BRVO.

Clinical Trial:: Helsinki's tenet

Keywords: vascular occlusion/vascular occlusive disease • macula/fovea • edema 
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