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K. R. Woodward, C. F. Brito, C. K. Doyle, R. H. Kardon, C. A. Johnson, M. Wall; Total Deviation Probability Plots for Size V Perimetry: A Comparison With Size III. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1620. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To develop databases from a common set of normal participants for empiric probability plots for Humphrey size V and III testing and compare with the STATPACTM size III (SITA) database.
We computed empiric probability plots from data collected from testing 60 normal participants (ages 40 - 78) on size III and size V testing. We then analyzed the probability plots of 120 Glaucoma patients (ages 38 - 81, mean deviation -6.67±4.4). We counted the number of test locations without and with loss at <1%, <2%, and <5% levels and compared the number of normal and abnormal test locations using size III vs. size V and size III results with Humphrey STATPACTM software results. Two-way repeated measures ANOVA was used to compare the number of normal and abnormal test locations among the three tests.
The graph shows the differences in the number of normal and abnormal test locations flagged by the three types of probability plots. There was no significant difference between size V and size III. At <2% and <5% loss, the number of abnormal test locations did not differ significantly among the tests. For the normal test locations, STATPACTM identified significantly more locations than size III; however, at <1% loss STATPACTM identified significantly fewer locations than size III.
Size V full threshold testing gives a similar number of abnormal test locations in glaucoma patients. This may be due to its better retest variability and tighter confidence limits.
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