May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Anatomical Outcomes Following Treatment for Retinal Pigment Epithelium Detachment Associated With Age-Related Macular Degeneration
H. H. Kim; P. E. Carvounis; R. P. A. Manzano; J. A. Fortun; B. Chan-Kai; T. A. Albini; E. R. Holz
Author Affiliations & Notes
  • H. H. Kim
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • P. E. Carvounis
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • R. P. A. Manzano
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • J. A. Fortun
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • B. Chan-Kai
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • T. A. Albini
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • E. R. Holz
    Ophthalmology, Baylor College of Medicine, Houston, Texas
  • Footnotes
    Commercial Relationships H.H. Kim, None; P.E. Carvounis, None; R.P.A. Manzano, None; J.A. Fortun, None; B. Chan-Kai, None; T.A. Albini, None; E.R. Holz, None.
  • Footnotes
    Support Research to Prevent Blindness
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1802. doi:
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      H. H. Kim, P. E. Carvounis, R. P. A. Manzano, J. A. Fortun, B. Chan-Kai, T. A. Albini, E. R. Holz; Anatomical Outcomes Following Treatment for Retinal Pigment Epithelium Detachment Associated With Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1802.

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Abstract

Purpose:: To report the frequency of retinal pigment epithelium tears following treatment of retinal pigment epithelium detachment (PED) associated age-related macular degeneration (ARMD) using photodynamic therapy (PDT), intravitreous triamcinolone acetonide (IVTK) or their combination (PDT+IVTK).

Methods:: Retrospective, comparative review of 33 eyes of 31 consecutive patients with ARMD-associated PEDs measuring more than 2/3 disc diameters, with initial visual acuity better than 20/200, treated with one or more sessions of PDT with Verteporfin, IVTK (4mg), or PDT+IVTK.

Results:: At 12 months, PEDs persisted in 80%, 87.5% and 50% of eyes in the PDT, IVTK and PDT+IVTK group (p=0.81) with RPE tears developing in 25% of eyes in the PDT+IVTK group compared to no eyes in the PDT or IVTK groups (p=0.04).

Conclusions:: PDT, IVTK, and PDT+IVTK are ineffective in resolving PEDs. PDT+IVTK results in a statistically significant increase in RPE tears compared to PDT or IVTK alone.

Keywords: age-related macular degeneration • retinal pigment epithelium • retina 
© 2007, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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