May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
A New Surgical Method for Sterile Corneal Ulceration
Author Affiliations & Notes
  • C. Longo
    Department of Ophthalmology, Insubria University, Varese, Italy
  • P. Sivelli
    Department of Ophthalmology, Insubria University, Varese, Italy
  • L. Geroli
    Department of Ophthalmology, Insubria University, Varese, Italy
  • L. Venco
    Department of Ophthalmology, Insubria University, Varese, Italy
  • P. Chelazzi
    Department of Ophthalmology, Insubria University, Varese, Italy
  • S. Donati
    Department of Ophthalmology, Insubria University, Varese, Italy
  • C. Azzolini
    Department of Ophthalmology, Insubria University, Varese, Italy
  • Footnotes
    Commercial Relationships C. Longo, None; P. Sivelli, None; L. Geroli, None; L. Venco, None; P. Chelazzi, None; S. Donati, None; C. Azzolini, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1882. doi:
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    • Get Citation

      C. Longo, P. Sivelli, L. Geroli, L. Venco, P. Chelazzi, S. Donati, C. Azzolini; A New Surgical Method for Sterile Corneal Ulceration. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1882.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To describe a new surgical method for the treatment of sterile corneal ulceration, using fibrin glue and a dedicated surgical forceps to apply and to lay the Amniotic Membrane (AM) on the corneal surface.

Methods:: Surgical treatment was performed with a two component fibrin glue (thrombin and fibrinogen) spread in two different surgical times. Amniotic membrane was washed in BSS, trimmed and layied down to the cornea by means of a dedicated forceps with specific opening claws. The patch of AM was soaked in thrombin, one of the two component of fibrin glue. The other component of fibrin glue, fibrinogen, was spread on corneal surface. The two components polymerized immediately within few seconds laying down the amniotic membrane on the cornea. A detached-stitch suture was not necessary so to fix the membrane on the eye surface

Results:: In early post surgical time we appreciated a regular and thin glue film under the membrane. We had a complete adhesion to the corneal surface without suture, also in 360° surface reconstruction where we implanted a big patch of amniotic membrane.

Conclusions:: The use of fibrin glue and specific experimental forceps made that surgical amniotic membrane transplant technique simpler and faster. We studied and performed this new experimental surgical tool to ameliorate our surgical performance. We applied particular care during that surgical application to obtain the best results.

Keywords: wound healing • cornea: epithelium • clinical (human) or epidemiologic studies: outcomes/complications 
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