May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Rapid Visual Rehabilitation After Boston K-Pro Implantation; One Week Post-Operative Vision From the Multicenter Boston Type 1 Keratoprosthesis Study
Author Affiliations & Notes
  • J. B. Ciolino
    Ophthalmology, Albany Medical College, Albany, New York
  • S. S. Khachikian
    Ophthalmology, Albany Medical College, Albany, New York
  • B. L. Zerbe
    Ophthalmology, Albany Medical College, Albany, New York
  • M. W. Belin
    Ophthalmology, Albany Medical College, Albany, New York
    Cornea Consultants of Albany, Slingerlands, New York
  • Boston Keratoprosthesis Type 1 Study Group
    Ophthalmology, Albany Medical College, Albany, New York
  • Footnotes
    Commercial Relationships J.B. Ciolino, None; S.S. Khachikian, None; B.L. Zerbe, None; M.W. Belin, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1892. doi:
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      J. B. Ciolino, S. S. Khachikian, B. L. Zerbe, M. W. Belin, Boston Keratoprosthesis Type 1 Study Group; Rapid Visual Rehabilitation After Boston K-Pro Implantation; One Week Post-Operative Vision From the Multicenter Boston Type 1 Keratoprosthesis Study. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1892.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To report the acute (1 week) post-operative visual rehabilitation in eyes implanted with the Boston Type 1 Keratoprothesis

Methods:: Forms containing pre-operative and post-operative visual acuity were collected at one central site from 17 different surgical sites. 2 year follow-up visual acuity and retention rates were previously reported.

Results:: 97 eyes (49%) from the total of 199 eyes in the study implanted have follow-up data within the first seven days postoperatively. Of these eyes, 59% had multiple failed grafts. The average number of prior graft failures was 2.8 with a range from 1 to 6. 14% of patients had a coexisting autoimmune disease and 9% had suffered a chemical injury. 12.3% obtained vision of 20/40 or better and 50.5% had vision of 20/200 or better. This is compared with 0% (20/40 or better) and 8.2% (20/200 or better) pre-operatively from the same patients.

Conclusions:: The Boston Type 1 Keratoprosthesis appears to offer patients who suffer corneal blindness and a poor prognosis for penetrating keratoplasty a rapid improvement in vision.

Keywords: keratoprostheses • cornea: clinical science • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials 
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