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J. B. Ciolino, S. S. Khachikian, B. L. Zerbe, M. W. Belin, Boston Keratoprosthesis Type 1 Study Group; Rapid Visual Rehabilitation After Boston K-Pro Implantation; One Week Post-Operative Vision From the Multicenter Boston Type 1 Keratoprosthesis Study. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1892.
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To report the acute (1 week) post-operative visual rehabilitation in eyes implanted with the Boston Type 1 Keratoprothesis
Forms containing pre-operative and post-operative visual acuity were collected at one central site from 17 different surgical sites. 2 year follow-up visual acuity and retention rates were previously reported.
97 eyes (49%) from the total of 199 eyes in the study implanted have follow-up data within the first seven days postoperatively. Of these eyes, 59% had multiple failed grafts. The average number of prior graft failures was 2.8 with a range from 1 to 6. 14% of patients had a coexisting autoimmune disease and 9% had suffered a chemical injury. 12.3% obtained vision of 20/40 or better and 50.5% had vision of 20/200 or better. This is compared with 0% (20/40 or better) and 8.2% (20/200 or better) pre-operatively from the same patients.
The Boston Type 1 Keratoprosthesis appears to offer patients who suffer corneal blindness and a poor prognosis for penetrating keratoplasty a rapid improvement in vision.
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