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F. Luciani, A. Giovannini, C. Brue, C. Mariotti, F. Frezza, S. Celani, E. Faloia; Resonance Raman Spectroscopic Measurement of Macular Carotenoids in Young Anorexic Females. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2132.
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Aim of the study is to detect Macular Carotenoids concentration in eyes of young females with anorexia and relate results to dietary factors.
Macular Carotenoids (MC) concentration was measured by a Raman spectroscope on young normal subjects (23 eyes, age ranging from 23 to 32 years old) and on young patients with Anorexia followed by the Clinic of Endocrinology of our Hospital (8 eyes, age 18-29 years old)We used: pupil dilation, self adjustment of the instrument and considered the best value out of three measures for each eye.Clinical data were collected on Body Mass index, dietary habits, consumption of fruit and vegetables, and smoking.
Mean Macular Carotenoids concentration was 2073,4±703 (SD) Raman counts in the anorexic group not significantly lower than 2227,87±590 (SD) in the control group (p<0,05).No correlation can be established with BMI.
while patients with anorexia show a wide range of severe nutritional deficits, Macular Carotenoids concentration was found similar to same age population.
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