May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Contrast Sensitivity, Color Perception and Macular Pigment in Patients With Age-Related Maculopathy and Blue Light-Filtering Intraocular Lens
Author Affiliations & Notes
  • S. P. Rothenbuehler
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • S. Wolf
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • E. Weyermann
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • N. Roeoesli
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • B. Frueh
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • S. Griesser
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • D. Goldblum
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • U. Wolf-Schnurrbusch
    Klinik und Poliklinik fuer Augenheilkunde, University of Bern Inselspital, Bern, Switzerland
  • Footnotes
    Commercial Relationships S.P. Rothenbuehler, Alcon Travel Grant, R; S. Wolf, None; E. Weyermann, None; N. Roeoesli, None; B. Frueh, None; S. Griesser, None; D. Goldblum, None; U. Wolf-Schnurrbusch, None.
  • Footnotes
    Support SNF 3200Bo-109962/1, Velux 303
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2151. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      S. P. Rothenbuehler, S. Wolf, E. Weyermann, N. Roeoesli, B. Frueh, S. Griesser, D. Goldblum, U. Wolf-Schnurrbusch; Contrast Sensitivity, Color Perception and Macular Pigment in Patients With Age-Related Maculopathy and Blue Light-Filtering Intraocular Lens. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2151.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose:: To compare postoperative visual acuity (VA), contrast sensitivity, color perception, and Macular Pigment Density (MPD) in patients with early age-related Maculopathy (ARM) after implantation of blue light-filtering AcrySof® Natural (SN60AT) or AcrySof® single-piece (SA60AT) intraocular lenses (IOLs).

Methods:: Inclusion criteria were an age above 50 years, early stage ARM (Rotterdam Classification, stages 1a to 3), willingness and possibility for examination 3 month postoperatively. Stage of ARM was classified by color fundus photos according to the Rotterdam Classification. All patients underwent best corrected distance VA (ETDRS), contrast sensitivity (Pelly-Robson chart), color perception (desaturated Farnsworth-Munsell Dichotomous D-15 Test), MPD measurements with a modified confocal scanning laser ophthalmoscope following a standard operation procedure. MPD maps were calculated from autofluorescence images recorded at 488nm and 514nm. MPD was quantified from MPD maps within 0.5 degree around the centre of the fovea.

Results:: We included in total 93 patients (41 male, 52 female) aged from 57 to 71 years (mean: 69.8 ± 5.6) into this prospective, randomized study. Forty-two (45.2%) patients with SN60AT and 51 (54.8%) patients with SA60AT IOL. Best corrected VA 3 month postoperatively was 20/20 or better in 95.2% of SN60AT eyes am 94.6% in SA60AT eyes. There were no statistically significant differences in contrast sensitivity scores or color perception. Mean MPD was 0.36 ± 0.21 density units (D.U.). There were no statistically significant differences in MPD values (SN60AT: 0.37 ± 0.23 D.U. vs. SA60AT: 0.38 ± 0.20 D.U.).

Conclusions:: The blue light-filtering AcrySof® Natural (SN60AT) IOL has postoperative comparable results with AcrySof® single-piece (SA60AT) IOL. A possible protective effect of blue light-filtering IOL for ARM and a predictive interpretation of our results have to be investigated in further studies. We hope to improve our understanding of the predisposing factors, clinical course and prognostic factors of ARM and ARMD.

Clinical Trial:: Ethics Committee Kanton Bern

Keywords: age-related macular degeneration • color vision • contrast sensitivity 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×