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A. Loewenstein, M. Goldstein, O. Rafaeli, A. Barak; A New Home-Monitoring-Amd-Perimeter for the Detection of CNV Onset. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2165.
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The HMP is a prototype of standalone portable PC-based perimetry device. 41 eyes (38 patients) with intermediate AMD underwent supervised examination session with the HMP at their home twice a week for 1 month. A tutorial was followed by 8 sessions. A personalized on-line algorithm adjusted the tests according to subject's performance. The acceptance criteria for a successful performance were that the patient managed to reach a hyperacuity sensitivity level of 0.16 degrees offset on horizontally (H) presented signals or 0.19 degrees offset on vertically (V) presented signals, and that the test was performed in a reliable manner.
88% percent (36/41 eyes) reached the required working level (≤0.16H or ≤0.19V) and performed the test reliably. 5 patients (5 eyes) did not meet the acceptance criteria. Following the tutorial sessions, all patients, including computer-illiterate ones, managed to operate the device. The performance of the patients while doing the tutorial improved from one practice session to the next .The online analysis, assisting the patient to reach their personalized working level, using "staircase method" was found to be efficient and most patients reached the required sensitivity level in 4-6 sessions.
The concept of home automated perimetry for intermediate AMD patients was validated successfully and can be used in the future generations of the device. This new home diagnostic device holds promise for early detection of CNV with better final outcome following newly developed and evolving treatment options.
www.clinicaltrials.gov NCT00359008 trial performed prior to registration requirements
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