May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Thickness Measurements of Serous Retinal Detachment With Choroidal Neovascularization
Author Affiliations & Notes
  • S. Ozawa
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • K. Ishikawa
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • Y. Ito
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • M. Kikuchi
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • H. Nishihara
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • T. Yamakoshi
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • Y. Hatta
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • H. Terasaki
    Ophthalmology, Nagoya Univ Sch of Medicine, Nagoya, Japan
  • Footnotes
    Commercial Relationships S. Ozawa, None; K. Ishikawa, None; Y. Ito, None; M. Kikuchi, None; H. Nishihara, None; T. Yamakoshi, None; Y. Hatta, None; H. Terasaki, None.
  • Footnotes
    Support Grants-in Aid 18791272(KI),16390497(HT),and 18390466(HT) from the Ministry of Education, Science, Sports and Culture, Japan.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2169. doi:https://doi.org/
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    • Get Citation

      S. Ozawa, K. Ishikawa, Y. Ito, M. Kikuchi, H. Nishihara, T. Yamakoshi, Y. Hatta, H. Terasaki; Thickness Measurements of Serous Retinal Detachment With Choroidal Neovascularization. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2169. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: We have published a computer program which can analyze the optical coherence tomographic (OCT) images of the retina and determine the retinal thickness manually. (Invest Ophthalmol Vis Sci2005;46: E-Abstract 1550) The purpose of this study was to compare the thickness of serous retinal detachments (SRDs) in eyes with age-related macular degeneration (AMD) to those with polypoidal choroidal vasculopathy (PCV) using our program.

Methods:: OCT was performed on 61 eyes with AMD and 53 eyes with PCV that had not have any previous therapy for choroidal neovascularization (CNV). Six radial scans of 6 mm length were obtained with the Fast Macular Thickness Map protocol of the Stratus OCT. The SRD thickness within the 3 mm diameter circle centered on the fovea was obtained by subtracting the thickness of the neurosensory retina from the distance from the inner surface of the retina to the retinal pigment epithelium.

Results:: SRDs were observed in 42 of the 61 eyes (69%) with AMD and in 36 of the 53 eyes (68%) with PCV. In the 78 eyes, the mean thickness of the SRD within the 3 mm diameter circle centered on the fovea was 31.9± 5.9 µm (mean±SEM) in the AMD group compared to 83.9±14.0 µm in the PCV group (P<0.01; Mann-Whitney,s U test). Three of 42 eyes (7%) in the AMD group had a SRD≥100 µm compared with 14 of 36 eyes (39%) in the PCV group (P< 0.01; Fisher exact probability test).

Conclusions:: The mean thickness of the SRD in the PCV group was greater than that in the AMD group. The incidence of large SRDs thickness was higher in the PCV group than in the AMD group.

Keywords: age-related macular degeneration • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
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